In recent years, significant research attention has been given to understanding the entanglements of culture and climate change in indigenous communities in global and Australian contexts.  However, while there is a growing body of knowledge on the threats and vulnerabilities posed by climate change to indigenous peoples and cultures, there is to date little substantive research on the ways that Australian Aboriginal people in remote, arid-zone communities themselves observe, perceive, experience, and act upon the changing climate.  This paper reports on a trans-disciplinary pilot study that begins to correct such deficits.  The research project had two principle aims.  The first was to investigate and document Aboriginal perceptions and understandings of climate change in an interior arid-zone region, namely the Upper Georgina River Basin (UGRB) located in far northwest Queensland, Australia. The second aim was to study the capacity of these communities to respond and adapt to the threat of climate change. After reporting on the findings of this project, this paper considers the extent to which Aboriginal communities in the UGRB can utilize culturally grounded knowledges and practices to engage in more meaningful dialogues about climate change with interlocutors from different cultural and epistemological backgrounds.  In particular, we examine the role of Aboriginal Knowledge as an important resource to help transform Aboriginal peoples’ perceptions about climate change, self-perceptions about their capacity to act in order to adapt to a changing environment, and the policy frameworks through which community resilience is fostered.